Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Therapeutic scarification, shadow pain, and integrative geriatric rehabilitation for chronic musculoskeletal pain in older adults in Cameroon: a prospective mixed-methods observational study.

Frontiers in pain research (Lausanne, Switzerland)·2026
Same author

Cognitive impairment is associated with disrupted motor planning in older adults.

Neuro-degenerative diseases·2026
Same author

Correction: Tango‑therapy vs physical exercise in older people with dementia; a randomized controlled trial.

BMC geriatrics·2026
Same author

Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation.

Frontiers in aging·2026
Same author

Institutional mechanisms excluding rehabilitation from medical education in Central Africa: A mixed-methods case study from Cameroon with implications for WHO regional strategy implementation.

Dialogues in health·2026
Same author

Balance and Gait Disorders in the Aged Population. Causes, Assessment and Management: A Literature Review.

Clinical interventions in aging·2025
Same journal

Soins. Gerontologie·2026
Same journal

[The role of geriatric telemonitoring in risk prevention: an analysis of interventions by a coordination unit].

Soins. Gerontologie·2026
Same journal

[Nursing expertise in home care within a mobile geriatric team].

Soins. Gerontologie·2026
Same journal

["Well-being in sight": using film to celebrate the life experiences of older adults].

Soins. Gerontologie·2026
Same journal

[Fostering Empathy in Geriatric Care: Film-Based Education with The Father].

Soins. Gerontologie·2026
Same journal

[The poetics of care, on the film Marguerite].

Soins. Gerontologie·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2026

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

[Walking and ageing].

France Mourey1

  • 1Université de Bourgogne, Gérontopôle, Centre gériatrique de Champmaillot, CHU de Dijon. france.mourey@u-bourgogne.fr

Soins. Gerontologie
|June 22, 2010
PubMed
Summary
This summary is machine-generated.

As people age, their walking patterns change, leading to slower speeds and shorter strides. Recognizing these common gait changes in the elderly helps healthcare providers tailor patient care.

More Related Videos

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
04:13

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults

Published on: February 8, 2019

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

Related Experiment Videos

Last Updated: Jun 12, 2026

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
04:13

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults

Published on: February 8, 2019

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

Area of Science:

  • Gerontology
  • Biomechanics
  • Kinesiology

Context:

  • Age-related physiological changes impact mobility.
  • Gait disturbances are common in the elderly population.
  • Understanding gait alterations is crucial for geriatric care.

Purpose:

  • To elucidate the typical changes in human gait associated with aging.
  • To identify key factors contributing to mobility issues in older adults.
  • To inform healthcare professionals about age-related gait modifications.

Summary:

  • Aging is insidiously associated with changes in gait, including reduced walking speed, shorter stride length, and increased double support time.
  • Four primary factors are frequently interconnected in the gait problems observed in the elderly.
  • Increased awareness of these factors allows for better adaptation of care strategies for geriatric patients.

Impact:

  • Enhanced understanding of age-related gait changes can lead to targeted interventions.
  • Improved mobility and fall prevention in the elderly population.
  • Facilitates personalized healthcare approaches for older adults experiencing gait difficulties.