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[Prediction of the GVHD after allo-HSCT by sequence similar matching method]
Dan-Dan Zhao1, Zhou-Yang Liu, Yong-Bin Cao
1Department of Hematology, 304th Clinical Division, Chinese PLA General Hospital, Beijing 100048 China.
Abstract:
This study was aimed to investigate the role of sequence similar matching (SSM) method in prediction of GVHD after HLA unmatched allogeneic hematopoietic stem cell transplantation (allo-HSCT). The data from 23 patients undergoing HLA unmatched allo-HSCT were analyzed and calculated by SSM method. The results showed that the incidence of acute and severe GVHD were significantly less in the allo-HSCT cases with total SSM value less than 55. In conclusion, the SSM method can be used to predict GVHD in the HLA-unmatched allogeneic hematopoietic stem cell transplantation.
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