Related Experiment Video
Updated: Jun 12, 2026

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
Published on: November 29, 2024
[Transfer factors in medical therapy]
Dolores J Sánchez-González1, Carlos A Sosa-Luna, Ismael Vásquez-Moctezuma
1Subsección de Biología Celular y Tisular, Escuela Médico Militar, Universidad del Ejército y Fuerza Aérea, México DF, México.
Transfer factor (TF) comprises messenger peptides from T lymphocytes that transfer immunity. This non-immunogenic substance is species-non-specific and can be used as adjuvant therapy.
Area of Science:
- Immunology
- Molecular Biology
Context:
- Transfer factor (TF) is derived from activated T lymphocytes.
- TF plays a role in cellular immunity, modulating naive lymphocytes.
Purpose:
- To describe the composition and properties of transfer factor.
- To highlight its potential therapeutic applications.
Summary:
- TF consists of messenger peptides, with specific antigen transfer factors (STF) between 3.5-5 kDa.
- TF extracts contain over 200 molecules (1-20 kDa) and possess a conserved amino acid sequence (LLYAQDL/VEDN), rendering them non-immunogenic and species-non-specific.
- TF can transfer immunity across species and is well-tolerated, lacking HL-A antigens.
Impact:
- TF's non-immunogenic and species-non-specific nature allows for broad application.
- TF can be utilized as an adjuvant therapy in various medical conditions.
- Facilitates interspecies immunity transfer and is easily prepared.
More Related Videos
Related Concept Videos
Therapeutic Drug Monitoring: Affecting Factors
Pharmacogenetics of Phase II Enzymes: N-acetyltransferase, Thiopurine S-methyltransferase, UDP-glucuronosyltransferase
Factors Affecting Drug Biotransformation: Biological
Species differences: Variations in enzyme systems across species can cause disparities in drug metabolism. For instance, humans may metabolize certain drugs faster than rodents, altering therapeutic effects.
Strain differences: Genetic variations within a species can result in differing enzyme activity, impacting drug response and toxicity. For example, some mouse strains may...
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

