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Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Bladder cancer in 2010: how far have we come?
Bruce L Jacobs1, Cheryl T Lee, James E Montie
1Department of Urology, University of Pitsburgh School of Medicine, 3471 Fifth Avenue, Pittsburgh, PA 15213-3233, USA. jacobsbl@upmc.edu
CA: a Cancer Journal for Clinicians
|June 23, 2010
Summary
Bladder cancer management involves variable treatment decisions, necessitating early detection of high-risk patients for improved outcomes. This review covers advances in bladder cancer detection, surveillance, and treatment.
Area of Science:
- Urology
- Oncology
- Cancer Research
Background:
- Bladder cancer is a significant health concern, ranking as the fourth most common cancer and eighth leading cause of cancer death in US men.
- Current bladder cancer management, including neoadjuvant chemotherapy and cystectomy timing, shows variability despite existing guidelines.
- The propensity for recurrence and progression in bladder cancer underscores the critical need for early identification of high-risk individuals.
Purpose of the Study:
- To review recent advancements in the detection of bladder cancer.
- To discuss improvements in the surveillance strategies for bladder cancer patients.
- To highlight progress in the treatment modalities for bladder cancer.
Main Methods:
- Literature review of recent studies on bladder cancer detection.
- Analysis of current surveillance protocols and their effectiveness.
- Evaluation of novel and established treatment approaches for bladder cancer.
Main Results:
- Emerging technologies offer improved accuracy in bladder cancer detection.
- Enhanced surveillance methods aid in the timely identification of recurrent or progressive disease.
- Advances in treatment, including neoadjuvant chemotherapy and surgical techniques, are refining patient management.
Conclusions:
- Early and accurate detection of high-risk bladder cancer patients is crucial for effective management.
- Continuous advancements in detection, surveillance, and treatment are vital for improving outcomes in bladder cancer.
- A comprehensive approach integrating these advances is necessary to address the challenges posed by bladder cancer recurrence and progression.
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