Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Production of Antibiotics01:27

Production of Antibiotics

Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...
Microbial Bioremediation of Plastics01:28

Microbial Bioremediation of Plastics

Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...
Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of lovastatin with immobilized Candida rugosa lipase in organic solvents: Effects of reaction conditions on initial rates.

Biotechnology and bioengineering·2008
Same author

The effect of trans sodium crocetinate (TSC) in a rat oleic acid model of acute lung injury.

Pulmonary pharmacology & therapeutics·2005
Same author

Esterification of fatty acids using nylon-immobilized lipase in n-hexane: kinetic parameters and chain-length effects.

Journal of biotechnology·2002
Same author

Trans-sodium crocetinate restores blood pressure, heart rate, and plasma lactate after hemorrhagic shock.

The Journal of trauma·2001
Same author

Asymmetric ketone reduction with immobilized yeast in hexane: biocatalyst deactivation and regeneration.

Biotechnology progress·2001
Same author

Intravenous crocetinate prolongs survival in a rat model of lethal hypoxemia.

Critical care medicine·2000

Related Experiment Video

Updated: Jun 12, 2026

Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests
09:42

Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests

Published on: September 28, 2021

Ethylene from penicillium digitatum.

A M Tanyolac1, J L Gainer

  • 1Department of Chemical Engineering University of Virginia Thornton Hall Charlottesville, VA 22901.

Biotechnology Progress
|June 23, 2010
PubMed
Summary
This summary is machine-generated.

This study explores producing ethylene, a bulk chemical, through fermentation using the fungus Penicillium digitatum. Adapting the fungus to submerged culture conditions is key for efficient ethylene biosynthesis.

More Related Videos

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials
08:21

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

Elucidating β-1,3-Glucanase and Peroxidase Physicochemical Properties of Wheat Cell Wall Defense Mechanism Against Diuraphis noxia Infestation
10:26

Elucidating β-1,3-Glucanase and Peroxidase Physicochemical Properties of Wheat Cell Wall Defense Mechanism Against Diuraphis noxia Infestation

Published on: July 26, 2024

Related Experiment Videos

Last Updated: Jun 12, 2026

Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests
09:42

Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests

Published on: September 28, 2021

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials
08:21

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

Elucidating β-1,3-Glucanase and Peroxidase Physicochemical Properties of Wheat Cell Wall Defense Mechanism Against Diuraphis noxia Infestation
10:26

Elucidating β-1,3-Glucanase and Peroxidase Physicochemical Properties of Wheat Cell Wall Defense Mechanism Against Diuraphis noxia Infestation

Published on: July 26, 2024

Area of Science:

  • Biotechnology
  • Industrial Microbiology
  • Chemical Engineering

Background:

  • Ethylene is a high-volume industrial chemical typically produced via steam cracking of hydrocarbons.
  • Fermentation offers a potential sustainable alternative for bulk chemical production.
  • Fungal fermentation presents opportunities for novel biosynthetic pathways.

Purpose of the Study:

  • To investigate the feasibility of producing ethylene using Penicillium digitatum.
  • To evaluate the impact of adapting Penicillium digitatum to submerged culture conditions.
  • To assess the potential of fungal fermentation for bulk chemical synthesis.

Main Methods:

  • Cultivation of Penicillium digitatum under varying submerged conditions.
  • Optimization of fermentation parameters for ethylene production.
  • Gas chromatography analysis for ethylene quantification.

Main Results:

  • Successful production of ethylene by Penicillium digitatum in submerged culture.
  • Demonstration of fungal adaptation influencing ethylene yield.
  • Identification of key parameters for enhancing fermentation-based ethylene synthesis.

Conclusions:

  • Penicillium digitatum is a viable microorganism for fermentative ethylene production.
  • Submerged culture adaptation is crucial for optimizing ethylene biosynthesis in fungi.
  • Fungal fermentation represents a promising bio-based route for sustainable bulk chemical manufacturing.