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Updated: Jun 12, 2026
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The ITS2 Database
Published on: March 12, 2012
DIVEIN: a web server to analyze phylogenies, sequence divergence, diversity, and informative sites
Wenjie Deng1, Brandon S Maust, David C Nickle
1Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Biotechniques
|June 24, 2010
Summary
DIVEIN is a web tool for automated phylogenetic analysis of DNA and protein sequences. It reconstructs key evolutionary sequences and provides diverse tools for genetic diversity and divergence studies.
Area of Science:
- Bioinformatics
- Computational Biology
- Evolutionary Biology
Background:
- Phylogenetic analysis is crucial for understanding evolutionary relationships.
- Automated tools are needed to streamline complex sequence analyses.
Purpose of the Study:
- To introduce DIVEIN, a web interface for automated phylogenetic and sequence analyses.
- To provide a comprehensive suite of tools for evolutionary parameter estimation and sequence reconstruction.
Main Methods:
- Utilizes aligned nucleotide and amino acid sequences.
- Employs various evolutionary models for phylogenetic tree estimation.
- Reconstructs consensus (CON), most recent common ancestor (MRCA), and center of tree (COT) sequences.
Main Results:
- DIVEIN automates the estimation of evolutionary parameters and phylogenetic trees.
- It offers tools for sequence alignment condensation, divergence computation, and genetic distance analysis.
- Graphical representations of trees, divergence, and diversity distributions are generated.
Conclusions:
- DIVEIN provides a user-friendly platform for in-depth phylogenetic and sequence analysis.
- The tool facilitates the study of genetic diversity and evolutionary relationships.
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