Related Experiment Video
Updated: Jun 12, 2026

09:32
Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
Published on: December 9, 2021
Endovascular Thermal Coagulation Using the Double-Helix GDC. Feasibility Study in Experimental Aneurysms
1University of Roma "La Sapienza", Italy and University of California at Davis, U.S.A - guidogdc@yahoo.com.
Summary
This study explored thermal coagulation for treating brain aneurysms. A novel device successfully occluded experimental aneurysms, suggesting potential for large and giant intracranial aneurysms.
Area of Science:
- Neurosurgery
- Biomedical Engineering
- Vascular Surgery
Background:
- Large and giant intracranial aneurysms pose significant treatment challenges.
- Current endovascular techniques have limitations for specific aneurysm subtypes.
Purpose of the Study:
- To investigate the feasibility of thermal coagulation for treating experimental aneurysms.
- To evaluate a novel device for endovascular aneurysm occlusion.
Main Methods:
- Experimental study on aneurysms.
- Application of radiofrequency electrical current for thermal coagulation.
- Utilized a novel double-helix Guglielmi Detachable Coil (GDC) device.
Main Results:
- Successful endovascular endosaccular thermal coagulation of experimental aneurysms.
- Demonstrated the efficacy of the radiofrequency current and novel device.
Conclusions:
- Thermal coagulation is a potential treatment modality for specific aneurysm subsets.
- The double-helix GDC device shows promise for occluding large and giant intracranial aneurysms.

