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Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
Metastatic cutaneous carcinosarcoma to the tongue
N Tanaka1, S Hidaka, M Yamamura
1Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, Japan. ntanaka@dent.osaka-u.ac.jp
International Journal of Oral and Maxillofacial Surgery
|June 24, 2010
Summary
This case report details an extremely rare instance of carcinosarcoma, a mixed malignant tumor, metastasizing to the tongue. The aggressive nature of this metastatic cancer led to rapid progression and a fatal outcome within two months.
Area of Science:
- Oncology
- Pathology
Background:
- Carcinosarcoma is a rare malignant neoplasm characterized by both carcinomatous and sarcomatous components.
- Metastasis of carcinosarcoma to the oral cavity, specifically the tongue, is exceptionally uncommon.
Observation:
- An 84-year-old female presented with a rapidly enlarging tongue mass.
- A history of occipital skin carcinosarcoma resection 9 months prior was noted.
- Histopathological examination confirmed the tongue mass as carcinosarcoma.
Findings:
- Positron Emission Tomography (PET) revealed widespread metastatic disease.
- The patient succumbed to the aggressive malignancy two months post-diagnosis.
Implications:
- This case represents the first documented instance of carcinosarcoma metastasizing to the tongue.
- Treatment challenges for aggressive oral cavity metastases are highlighted, underscoring the need for further research.
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