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Related Concept Videos

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Related Experiment Video

Updated: Jun 12, 2026

Murine Mesenteric Lymphadenectomy for Selective Disruption of Lymphatic Communication with Region-Specific Gut
07:27

Murine Mesenteric Lymphadenectomy for Selective Disruption of Lymphatic Communication with Region-Specific Gut

Published on: December 30, 2025

Mesenteric lymph node cavitation syndrome.

Hugh James Freeman1

  • 1Department of Medicine (Gastroenterology), University of British Columbia Hospital, 2211 Wesbrook Mall, Vancouver, BC, V6T 1W5, Canada. hugfree@shaw.ca

World Journal of Gastroenterology
|June 24, 2010
PubMed
Summary
This summary is machine-generated.

Mesenteric lymph node cavitation syndrome, a condition linked to celiac disease, involves lymph node necrosis and splenic hypofunction. Early detection via imaging may improve prognosis and understanding of this serious gastrointestinal disorder.

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The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport
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The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport

Published on: March 6, 2015

Area of Science:

  • Gastroenterology
  • Pathology
  • Radiology

Background:

  • Mesenteric lymph node cavitation syndrome is characterized by central necrosis of mesenteric lymph nodes.
  • It can be associated with celiac disease or refractory sprue-like intestinal disease.
  • Splenic hypofunction may also be a feature of this syndrome.

Purpose of the Study:

  • To describe the mesenteric lymph node cavitation syndrome.
  • To highlight its association with celiac disease and potential complications.
  • To emphasize the role of modern imaging in early detection and understanding.

Main Methods:

  • Review of clinical presentations and imaging findings associated with mesenteric lymph node cavitation syndrome.
  • Correlation of syndrome development with celiac disease and other intestinal disorders.
  • Discussion of potential diagnostic and prognostic implications.

Main Results:

  • Mesenteric lymph node cavitation syndrome indicates a poor prognosis in celiac disease.
  • Associated complications include sepsis, malignancy (especially T-cell lymphoma), and significant mortality.
  • Modern abdominal imaging may facilitate earlier detection.

Conclusions:

  • Mesenteric lymph node cavitation syndrome is a serious complication of celiac disease with poor prognostic implications.
  • Early diagnosis through advanced imaging could lead to improved patient outcomes.
  • Further research into the pathogenesis of this syndrome is warranted.