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Relationship between oral malodor and the menstrual cycle
A Kawamoto1, N Sugano, M Motohashi
1Dental Hygienist Section, Nihon University Dental Hospital, Tokyo, Japan. imanaga@dent.nihon-u.ac.jp
Journal of Periodontal Research
|June 25, 2010
Summary
Menstrual cycle phases significantly impact periodontal disease. Women with periodontitis experienced increased volatile sulfur compounds (VSC), bleeding on probing (BOP), and Prevotella intermedia during ovulation.
Area of Science:
- Periodontology
- Oral Microbiology
- Endocrinology
Background:
- Sex hormones are implicated in periodontal disease pathogenesis.
- Menstrual cycle hormonal fluctuations may influence oral health.
- Understanding these changes is crucial for managing periodontal disease in women.
Purpose of the Study:
- To investigate changes in volatile sulfur compounds (VSC), clinical parameters, and bacterial levels during the menstrual cycle.
- To compare these changes between women with periodontitis and periodontally healthy women.
Main Methods:
- Study included 10 women with periodontitis and 12 healthy women.
- Clinical and bacterial measurements were taken during the follicular and ovulation phases.
- Volatile sulfur compounds (VSC) and Prevotella intermedia levels were quantified.
Main Results:
- Bleeding on probing (BOP) increased significantly during ovulation in periodontitis subjects.
- Volatile sulfur compounds (VSC) levels were 2.2-fold higher during ovulation in periodontitis subjects.
- Prevotella intermedia and VSC levels correlated with increased BOP during ovulation in periodontitis patients.
Conclusions:
- The menstrual cycle influences VSC levels, BOP, and Prevotella intermedia in women with periodontitis.
- Hormonal changes during the menstrual cycle may exacerbate periodontal disease activity.
- These findings highlight the importance of considering the menstrual cycle in periodontal care.
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