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[Study on extraction of anti-diabetes active constituents from Potentilla chinesis]
Chuan Zhao1, Sheng-an Tang, Hong-quan Duan
1Tianjin Research Center of Basic Medical Science, School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China.
Objective:
To study the extraction technology of anti-diabetes active constituents from Potentilla chinesis.
Methods:
Through single factor test, the effects of factors such as concentration of ethanol, temperature, ratio of liquid-solid, extraction time and times of extraction were investigated. Through orthogonal experiment, the optimal conditions of extraction were obtained on the basis of single factor test.
Results:
The optimum extraction conditions of Potentilla flavone from P. chinesis were determined as follows: refluxing for 3 times, 1.5 hours each time, and 8-6-6 for the multiple of 60% EtOH and material.
Conclusion:
The extraction process is stable and suitable for industry.