Labdanes and sucrose esters from Physalis sordida
Related Experiment Video
Updated: Jun 12, 2026

New Methods to Study Gustatory Coding
Published on: June 29, 2017
Ana-L Pérez-Castorena1, Mahinda Martínez, Emma Maldonado
1Instituto de Quimica, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad Universitaria, Coyoacan 04510, D.F., Mexico. alperezc@servidor.unam.mx
Abstract:
Eight new compounds, labdanes 2-4, homoergostane 10, and sucrose esters 12-15, were isolated from aerial parts of Physalis sordida together with several known compounds. Structures of the new compounds were elucidated using spectroscopic evidence and chemical transformations. The structure of 10 was confirmed by X-ray crystallographic analysis of its methyl ester. Anti-inflammatory activity of compounds 1, 2, 4, 5, and 12-15 was evaluated using the TPA-induced mouse ear edema test. Compounds 12 (IC(50) 0.26 mumol/ear) and 15 (IC(50) 0.24 mumol/ear) showed anti-inflammatory activity similar to that of indomethacin (IC(50) 0.24 mumol/ear).
Related Concept Videos
Alkylation of β-Diester Enolates: Malonic Ester Synthesis
β-Dicarbonyl Compounds via Crossed Claisen Condensations
Production of Organic Acids
Biosynthesis of Polysaccharides
Sugars as Energy Storage Molecules
Sugars as Energy Storage Molecules

