Related Experiment Video
Updated: Mar 2, 2026
06:37
An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
921
Xanthogranulomatous pyelonephritis in an adolescent
David Chalmers1, Sarah Marietti, Christina Kim
1Department of Urology, Connecticut Children’s Medical Center, Hartford, Connecticut 06106, USA.
Urology
|June 29, 2010
Summary
Xanthogranulomatous pyelonephritis is a rare pediatric kidney disease. A recent unsterile tattoo likely caused methicillin-resistant Staphylococcus aureus infection in a teen boy.
Area of Science:
- Nephrology
- Pediatric Urology
- Infectious Diseases
Background:
- Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic, inflammatory kidney disease.
- It is seldom diagnosed in the pediatric population, making pediatric cases noteworthy.
Observation:
- A 16-year-old male presented with fever, microscopic hematuria, and an enlarging cystic renal mass.
- No renal stones or other risk factors were identified, except for a recent tattoo using unsterile equipment.
Findings:
- Differential diagnoses included Wilms tumor, necessitating surgical exploration and nephrectomy.
- Histopathology confirmed Xanthogranulomatous pyelonephritis, with cultures identifying methicillin-resistant Staphylococcus aureus (MRSA).
Implications:
- This case suggests a potential link between unsterile tattooing practices and the development of XGP in adolescents.
- Bacterial seeding from contaminated tattoo equipment may be an underrecognized etiology for pediatric kidney infections.
Related Concept Videos
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
538
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
538
01:22Imaging Studies V: Intravenous Urography and Retrograde Pyelography
2.0K
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
2.0K
01:26Kidney Transplant II: Surgical Procedure
581
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
581
01:24Nephrotic Syndrome I : Introduction
779
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
779
01:27Acute Pyelonephritis I: Introduction
878
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
878
01:25Urinary Tract Infection II: Pathophysiology
911
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
911