Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Menopause01:28

Menopause

3.6K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
3.6K
Complementary DNA01:44

Complementary DNA

31.4K
Overview
31.4K
Alternative RNA Splicing02:18

Alternative RNA Splicing

24.8K
Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
24.8K
Alternative RNA Splicing02:18

Alternative RNA Splicing

5.0K
No description available
5.0K
Null and Alternative Hypotheses01:16

Null and Alternative Hypotheses

12.5K
The actual hypothesis testing begins by considering two hypotheses. They are termed  the null hypothesis and the alternative hypothesis. These hypotheses contain opposing viewpoints.
The null hypothesis, denoted by H0 is a statement of no difference between the variables—they are not related. This can often be considered the status quo. As  a result if you cannot accept the null, it requires some action.
The alternative hypothesis, denoted by H1 or Ha, is a claim about the...
12.5K
Gene Therapy00:59

Gene Therapy

27.4K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Authoritarian attitudes and the perceived scientific legitimacy of anthroposophic medicine: A survey of attitudes on complementary and alternative medicine in Austria.

PloS one·2026
Same author

Trials and tribulations of responsible people trying to uphold scientific standards.

Research integrity and peer review·2026
Same author

WHO's category mistake.

Lancet (London, England)·2025
Same author

Spinal manipulations for migraine: an updated systematic review and meta-analysis of randomized clinical trials.

Systematic reviews·2024
Same author

Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis.

Diseases (Basel, Switzerland)·2024
Same author

Is Craniosacral Therapy Effective? A Systematic Review and Meta-Analysis.

Healthcare (Basel, Switzerland)·2024

Related Experiment Video

Updated: Jan 27, 2026

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD
04:03

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Published on: September 27, 2024

1.3K

Alternative and complementary therapies for the menopause.

Francesca Borrelli1, Edzard Ernst

  • 1Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy. franborr@unina.it

Maturitas
|June 29, 2010
PubMed
Summary

Complementary and alternative medicine (CAM) shows promise for menopausal symptom relief, particularly black cohosh for hot flashes and certain supplements for cholesterol and bone health. However, more research is needed for other CAM therapies.

More Related Videos

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
03:56

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

1.2K
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

12.8K

Related Experiment Videos

Last Updated: Jan 27, 2026

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD
04:03

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Published on: September 27, 2024

1.3K
Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
03:56

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

1.2K
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

12.8K

Area of Science:

  • Integrative medicine and women's health.
  • Evidence-based complementary therapies.

Background:

  • Increasing use of complementary and alternative medicine (CAM) by menopausal women.
  • Need for evidence-based evaluation of CAM for menopausal symptom management.

Purpose of the Study:

  • To review existing evidence on CAM for menopausal symptoms.
  • To assess the efficacy of various CAM interventions.

Main Methods:

  • Systematic review of systematic reviews, randomized controlled trials (RCTs), and epidemiological studies.
  • Analysis of evidence for phytosterols, fiber, vitamin K, calcium, vitamin D, exercise, black cohosh, phytoestrogens, probiotics, prebiotics, acupuncture, homeopathy, and DHEA-S.

Main Results:

  • Phytosterols, phytostanols, and fiber show benefits for cholesterol reduction in postmenopausal women.
  • Vitamin K, calcium/vitamin D, and weight-bearing exercise help reduce bone mineral density loss and fractures.
  • Black cohosh is effective for hot flashes in early menopause.
  • Phytoestrogens have minimal effect on hot flashes but benefit lipids and bone health.
  • Evidence for probiotics, prebiotics, acupuncture, homeopathy, and DHEA-S is limited and unconvincing due to scarce RCTs.

Conclusions:

  • Certain CAM therapies, like black cohosh and specific supplements, offer benefits for menopausal symptoms and related health issues.
  • More rigorous randomized controlled trials are essential to validate the effectiveness of many commonly used CAM treatments.
  • Evidence-based guidance is needed for menopausal women seeking CAM options.