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Updated: Jun 11, 2026

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
Published on: September 9, 2016
Arabinosylated glycopeptide hormones: new insights into CLAVATA3 structure
Hidefumi Shinohara1, Yoshikatsu Matsubayashi
1Graduate School of Bio-Agricultural Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan.
Abstract:
Secreted peptides are now recognized as important members of hormones that coordinate and specify cellular functions in plants. Recent accumulating evidence shows that secreted peptide hormones are often post-translationally modified, and such modification is critical for their function. In this review, we highlight hydroxyproline arabinosylation, which has been found in several peptide hormones including CLAVATA3 (CLV3), a key peptide controlling stem cell renewal and differentiation in Arabidopsis shoot apical meristem. Arabinosylation of CLV3 is important for its biological activity and for high-affinity binding to its receptor, CLV1. We discuss the physiological functions of known glycopeptide hormones, the structural information on sugar chains, and possible mechanisms of glycosylation.
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