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Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format
05:58

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Recurrence of achondrogenesis type 2 in sibs: Additional evidence for germline mosaicism

Jessica M Comstock1, Angelica R Putnam, Nikhil Sangle

  • 1Division of Pediatric Pathology, Department of Pathology, University of Utah, Utah, USA. jessica.comstock@imail.org

American Journal of Medical Genetics. Part A
|June 29, 2010
PubMed

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Nondisjunction01:29

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Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
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Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...
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