PHACE Syndrome: Persistent Fetal Vascular Anomalies. A Case Report

Area of Science:

• Neurocutaneous disorders
• Vascular anomalies
• Medical case reports

Background:

• PHACE syndrome is a complex neurocutaneous disorder characterized by specific malformations.
• It typically presents in infancy with a defined set of features.
• Late-onset or unusual presentations are rare.

Purpose of the Study:

• To report an unusual case of PHACE syndrome.
• To describe a complete expression of PHACE syndrome in an adult.
• To highlight persistent fetal vascular anomalies in this context.

Main Methods:

• Case report analysis
• Clinical examination
• Review of medical literature

Main Results:

• A 55-year-old woman presented with complete PHACE syndrome.
• The patient exhibited large bilateral facial and neck hemangiomas.
• Posterior fossa circulation insufficiency and persistent fetal vascular anomalies were noted.

Conclusions:

• PHACE syndrome can manifest with persistent fetal vascular anomalies in adulthood.
• This case expands the known spectrum of PHACE syndrome presentation.
• Adult-onset PHACE syndrome requires consideration in complex vascular and malformation cases.