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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Related Experiment Video

Updated: Jun 11, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
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Electronically controlled coherent linear optical sampling for optical coherence tomography.

Stefan Kray1, Felix Spöler, Thomas Hellerer

  • 1Institute of Semiconductor Electronics, RWTH Aachen University, Aachen, Germany. kray@iht.rwth-aachen.de

Optics Express
|July 1, 2010
PubMed
Summary

We demonstrate electronically controlled linear optical sampling for low coherence interferometry and optical coherence tomography. This method overcomes previous repetition rate limitations for advanced optical imaging and characterization.

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Area of Science:

  • Optics and Photonics
  • Biomedical Imaging
  • Laser Technology

Background:

  • Low coherence interferometry (LCI) and optical coherence tomography (OCT) are crucial for high-resolution imaging.
  • Previous implementations faced limitations due to repetition rate constraints in optical sampling techniques.
  • Asynchronous optical sampling often introduced complexities and limitations.

Purpose of the Study:

  • To demonstrate electronically controlled coherent linear optical sampling for LCI and OCT.
  • To overcome repetition rate limitations inherent in prior optical sampling methods.
  • To enable adjustable scanning ranges and rates for enhanced interferometric measurements.

Main Methods:

  • Utilized two commercial mode-locked fiber lasers with synchronized repetition rates.
  • Implemented full electronic control over the mutual time delay between laser pulse trains.
  • Integrated the linear optical sampling scheme into an interferometric setup.

Main Results:

  • Successfully demonstrated electronically controlled coherent linear optical sampling.
  • Overcame repetition rate limitations, enabling higher flexibility in scanning.
  • Achieved adjustable scanning ranges and rates through electronic delay control.
  • Applied the technique with broad spectral bandwidths for LCI, filter characterization, and 2D/3D OCT imaging.

Conclusions:

  • Electronically controlled coherent linear optical sampling offers a robust solution for LCI and OCT.
  • This technique provides enhanced control and flexibility, overcoming previous technological barriers.
  • The method is versatile, applicable to various optical measurements and imaging modalities.