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Updated: Jun 11, 2026

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
The correlation between left ventricular failure and right ventricular systolic dysfunction occurring in
Ji Yeon Hong1, Dae-Gyun Park, Jong Jin Yoo
1Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.
Half of patients with thyrotoxicosis-induced heart failure also have right ventricular dysfunction (RVD). This RVD is not secondary to left ventricular dysfunction (LVD), as clinical and hemodynamic factors showed no differences between groups.
Area of Science:
- Cardiology
- Endocrinology
- Internal Medicine
Background:
- Thyrotoxicosis rarely causes heart failure, often involving left ventricular dysfunction (LVD).
- Right ventricular dysfunction (RVD) in thyrotoxicosis is infrequently reported, and its relationship with LVD is poorly understood.
Purpose of the Study:
- To investigate the prevalence and characteristics of right ventricular dysfunction (RVD) in patients with thyrotoxicosis-associated left ventricular dysfunction (LVD).
- To determine if RVD is associated with specific clinical or hemodynamic factors in this patient population.
Main Methods:
- A cohort of 12 patients with thyrotoxicosis, heart failure, and LVD (left ventricular ejection fraction <40%) were enrolled.
- Patients were categorized into two groups: Group I with RVD (tricuspid annular plane excursion <15 mm) and Group II without RVD.
- Clinical features, laboratory variables, and echocardiographic parameters were compared between groups.
Main Results:
- Right ventricular dysfunction (RVD) was identified in 50% of the patients.
- No significant differences were observed in clinical features, laboratory results, or echocardiographic parameters (including atrial fibrillation, heart rate, LVEF, or TRPPG) between patients with and without RVD.
- Following antithyroid treatment, all patients achieved an euthyroid state, and both left and right ventricular functions recovered without significant differences in recovery times or heart rate changes between groups.
Conclusions:
- Right ventricular dysfunction (RVD) frequently coexists with thyrotoxicosis-associated left ventricular dysfunction (LVD).
- The absence of differences in clinical and hemodynamic parameters suggests that RVD is not a direct consequence of LVD in thyrotoxicosis.
- Further research is warranted to elucidate the specific mechanisms underlying RVD in thyrotoxicosis.
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