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Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo
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Mesenchymal Stem Cells Sense Three Dimensional Type I Collagen through Discoidin Domain Receptor 1

A W Lund1, J P Stegemann, G E Plopper

  • 1Department of Biology, Rensselaer Polytechnic Institute, Troy, NY.

The Open Stem Cell Journal
|July 1, 2010
PubMed
Summary

Discoidin domain receptor 1 (DDR1) links mesenchymal stem cells to their 3D extracellular matrix environment. DDR1 regulates stem cell differentiation and matrix organization, impacting osteogenesis.

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