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Updated: Jun 11, 2026

Fabrication of Antibacterial Graphene Oxide/Copper Nanocomposites
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Graphene-based antibacterial paper.

Wenbing Hu1, Cheng Peng, Weijie Luo

  • 1Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, People's Republic of China.

ACS Nano
|July 3, 2010
PubMed
Summary
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Graphene oxide and reduced graphene oxide nanosheets show strong antibacterial activity against E. coli. These graphene materials can be fabricated into flexible paper for potential environmental and clinical applications.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Graphene, a single layer of carbon atoms, exhibits unique properties with diverse applications.
  • Water-dispersible graphene derivatives, such as graphene oxide (GO) and reduced graphene oxide (rGO), are being explored for various uses.

Purpose of the Study:

  • To investigate the antibacterial activity of graphene oxide (GO) and reduced graphene oxide (rGO) nanosheets.
  • To assess the potential of these graphene nanomaterials in environmental and clinical settings.

Main Methods:

  • Synthesis and characterization of water-dispersible GO and rGO nanosheets.
  • Evaluation of antibacterial activity against E. coli.
  • Fabrication of freestanding GO and rGO paper via vacuum filtration.

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  • Assessment of cytotoxicity.

    • Main Results:

    • GO and rGO nanosheets effectively inhibited the growth of E. coli bacteria.
    • These graphene materials demonstrated minimal cytotoxicity.
    • Macroscopic freestanding GO and rGO paper were successfully fabricated using vacuum filtration.

    Conclusions:

    • Graphene oxide and reduced graphene oxide possess significant antibacterial properties against E. coli.
    • The ease of fabrication and low cost of GO paper suggest promising environmental and clinical applications.
    • Graphene-based nanomaterials represent a novel class of materials for antibacterial interventions.