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Updated: Jun 11, 2026

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Unilateral failures in bilateral microvascular breast reconstruction
Samir S Rao1, Pranay M Parikh, Jesse A Goldstein
1Washington, D.C. From the Department of Plastic Surgery, Georgetown University Hospital.
Plastic and Reconstructive Surgery
|July 3, 2010
Summary
Unilateral flap failure in bilateral breast reconstruction is more common than in unilateral cases. However, prosthetic reconstruction techniques can lead to successful outcomes even after free flap failure.
Area of Science:
- Plastic Surgery
- Oncology
- Microsurgery
Background:
- Bilateral prophylactic mastectomy rates have risen, increasing the need for bilateral microvascular breast reconstruction.
- Data on unilateral flap failure in these complex reconstructions is limited.
- Effective strategies for managing flap failure are essential for optimal patient outcomes.
Purpose of the Study:
- To analyze the incidence and causes of unilateral flap failure in simultaneous bilateral microvascular breast reconstructions.
- To evaluate the techniques used for secondary reconstruction following flap failure.
- To provide insights into managing challenges in bilateral breast reconstruction.
Main Methods:
- Retrospective review of simultaneous bilateral microvascular breast reconstructions (July 1999 - July 2008).
- Identification and analysis of flap failures, including operative parameters and causes.
- Review of secondary reconstruction techniques for failed flaps.
Main Results:
- 171 patients underwent 342 bilateral microvascular breast reconstructions.
- Overall flap failure rate was 3.5% (12 of 342 flaps).
- Unilateral flap failure rate was 2.1%; causes included venous insufficiency and perforator issues. No bilateral failures occurred.
Conclusions:
- Flap failure is more frequent in bilateral than unilateral breast reconstructions due to donor site constraints.
- Despite free flap failure, successful bilateral reconstruction is achievable using prosthetic techniques.
- Secondary reconstruction with tissue expanders and implants is a viable option after flap loss.
