Infectious crystalline keratopathy treated with intrastromal antibiotics

An 84-year-old white female with nonprogressive conjunctival scarring developed infectious crystalline keratopathy (ICK) recalcitrant to topical therapy. After determination of the causative organism's antibiotic sensitivities, superficial keratectomy was performed with intrastromal corneal infiltration of cefuroxime into the affected cornea. Postoperatively, the ICK resolved completely, leading to an improvement in visual acuity and a reduction in ocular irritation. This case highlights the importance of a surgical approach in ICK and also demonstrates the possible benefit of a novel use of intracorneal antibiotics as an adjunct.