Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Essential Minerals for Bone Health

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

Role of Vitamins in Maintaining Bone Health

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...

Regulation of Stroke Volume

Regulation of Stroke Volume

The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...

Blood and Nerve Supply to the Bones

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...

Spongy Bone

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...

Bone as Supporting Connective Tissue

Bone as Supporting Connective Tissue

Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts— that give the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Anticholinergic Medication Burden Scales: A Systematic Review.

Journal of the American Geriatrics Society·2026

Same author

Sex and Ethnic Disparities in Stroke Revascularisation Treatments and Post-Stroke Outcomes in Patients with Heart Failure: A National Inpatient Sample Study.

Journal of clinical medicine·2025

Same author

Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial.

Circulation. Heart failure·2025

Same author

Evaluating the Anticholinergic Burden in Older Patients: Comprehensive Insights from a Nationwide Survey Among Emergency Medicine Specialists in the UK.

Geriatrics (Basel, Switzerland)·2025

Same author

Treatment patterns of romosozumab in postmenopausal women with severe osteoporosis in Denmark: findings from the ROmosozumab in Scandinavia real-world Evidence Study (ROSES).

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2025

Same author

Emergency department attendance stratified by cause and frailty status: A national retrospective cohort study.

Geriatrics & gerontology international·2025

Search research articles

Related Experiment Video

Updated: Jun 11, 2026

Multimodal Approach to Assess Bone Regeneration and Scaffold Performance

Multimodal Approach to Assess Bone Regeneration and Scaffold Performance

Published on: February 13, 2026

The complex mutual connection between stroke and bone health.

Alireza Moayyeri¹, Yasir A Alrawi, Phyo K Myint

¹Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. am700@cam.ac.uk

Archives of Biochemistry and Biophysics

|July 6, 2010

Summary

This summary is machine-generated.

Stroke and osteoporosis are common in the elderly. This review explores their link, focusing on how stroke impacts bone health and offers strategies for managing osteoporosis in stroke survivors.

Related Experiment Videos

Last Updated: Jun 11, 2026

Multimodal Approach to Assess Bone Regeneration and Scaffold Performance

Multimodal Approach to Assess Bone Regeneration and Scaffold Performance

Published on: February 13, 2026

Area of Science:

Gerontology
Neurology
Orthopedics

Background:

Stroke and osteoporosis are highly prevalent in the aging global population.
Both conditions share common risk factors and influence each other, particularly stroke's effect on bone health.

Purpose of the Study:

To review the pathophysiology of stroke and osteoporosis.
To examine the bidirectional relationship between stroke and bone health.
To provide evidence-based recommendations for improving bone health in stroke patients.

Main Methods:

Literature review of existing studies on stroke, osteoporosis, and their interrelation.
Analysis of etiological and pathophysiological mechanisms.
Synthesis of current evidence regarding the impact of stroke on bone health.

Main Results:

Stroke significantly impacts bone health, increasing osteoporosis risk.
Evidence suggests a complex interplay between the two conditions.
Shared risk factors contribute to their co-occurrence.

Conclusions:

Stroke survivors are at increased risk of developing osteoporosis.
Further research is needed to fully elucidate the mechanisms.
Proactive management of bone health is crucial for stroke patients.