Development of a new disintegration method for orally disintegrating tablets

Ryo Kakutani1, Hiroyuki Muro, Tadashi Makino

  • 1Novel Pharmaceutical Labs, Kyoto Pharmaceutical Industries, Ltd., Kyoto, Japan. kakutani@kyoto-pharm.co.jp

Summary

A new Kyoto-model disintegration (KYO) method accurately predicts oral disintegrative properties of orally disintegrating tablets (ODTs). This physical assessment method correlates well with human sensory tests, aiding ODT development and quality control.

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