Related Experiment Video
Updated: Jun 11, 2026

Preparation of Giant Vesicles Encapsulating Microspheres by Centrifugation of a Water-in-oil Emulsion
Published on: January 24, 2017
Controlled incorporation of particles into the central portion of vesicle walls
1Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 2K6, Canada.
Abstract:
Vesicles have attracted considerable attention recently because of many potential applications as well as intrinsic interest in the structures. The incorporation of various particles into vesicle walls has also received attention. One of the unsolved problems, in this context, is the controlled incorporation of particles into only the central portion of the vesicle walls, i.e. approximately halfway between the external and internal interfaces. In this paper, we describe a general method for the incorporation of particles into only the central portion, i.e. central 10-20%, of the vesicle walls. The strategy involves the use, as coatings on the particles, of diblock copolymers of a structure similar to that of the vesicle formers, which allows the particles to be preferentially localized in the central portion of the walls.
Related Concept Videos
Intralumenal Vesicles and Multivesicular Bodies
Pinching-off of Coated Vesicles
Clathrin Coated Vesicles
Vesicular Tubular Clusters
With the help of motor proteins such...
Fusion of Secretory Vesicles with the Plasma Membrane
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
COP Coated Vesicles

