[Osteocalcin in rheumatoid arthritis--a marker for accelerated bone turnover in late-onset rheumatoid arthritis?]

Increased levels of OC can be detected in late RA with high disease activity, whereas no major bone impairment is detectable in early and advanced stages of RA suggesting a more serious bone involvement in this form of the disease. OC appears to be a good marker to identify osteopenia in late onset active RA.