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Updated: Mar 16, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Application of a high-performance liquid chromatography coulometric method for the estimation of mebendazole and its
P Betto1, M Gianbenedetti, F Ponti
1Istituto Superior di Sanità, Laboratorio di Chimica del Farmaco, Rome, Italy.
Abstract:
A novel, sensitive high-performance liquid chromatographic method, making use of coulometric detection, for the estimation of mebendazole and its metabolites in the sera of eight hydatidosis patients was devised. Recovery rates, precision, accuracy and sensitivity for each compound are reported and compared with those of the previously published methods.
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