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Oral calcifying fibrous pseudotumor: case analysis and review
Diana M Bell1, Roupen H Dekmezian, Shaista A Husain
1Department of Pathology, Unit 85, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
Head and Neck Pathology
|July 9, 2010
Summary
Calcifying fibrous pseudotumor (CFT) is a rare, benign soft-tissue lesion. This case study details a gingival and hard palate CFT, discussing its differential diagnosis and management.
Area of Science:
- Pathology
- Oncology
Background:
- Calcifying fibrous pseudotumor (CFT) is a rare soft-tissue neoplasm.
- It is characterized by lymphoplasmacytic infiltration, collagenization, and calcifications.
Observation:
- A 29-year-old woman presented with a 7-cm mass on the right upper gingiva and hard palate.
- The lesion's location is unusual for CFT, which typically occurs in deeper soft tissues or serosal locations.
Findings:
- Histological examination revealed features consistent with CFT.
- The differential diagnosis included other oral spindle cell lesions like desmoid fibromatosis and solitary fibrous tumor.
Implications:
- Simple excision with clear margins is the recommended treatment for CFT.
- The prognosis is generally good with a low risk of local recurrence.