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Updated: Jun 11, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
An experimental study of prospective memory in obsessive-compulsive disorder
Mihaly Racsmany1, Gyula Demeter, Katalin Csigo
1Department of Cognitive Science, Budapest University of Technology and Economics, Budapest, Hungary. racsmany@cogsci.bme.hu
Obsessive-compulsive disorder (OCD) patients show impaired prospective memory (PM) function. This deficit stems from overmonitoring stimuli for PM cues, impacting task performance and reaction times.
Area of Science:
- Cognitive Psychology
- Neuroscience
- Psychiatry
Background:
- Obsessive-compulsive disorder (OCD) is a mental health condition characterized by obsessions and compulsions.
- Prospective memory (PM), the ability to remember to perform an intended action in the future, is crucial for daily functioning.
- Dysfunctions in cognitive processes, including PM, are increasingly recognized in psychiatric disorders like OCD.
Purpose of the Study:
- To investigate prospective memory (PM) function in individuals diagnosed with obsessive-compulsive disorder (OCD).
- To compare PM task performance between OCD patients and healthy adults.
- To identify the underlying cognitive mechanisms contributing to potential PM deficits in OCD.
Main Methods:
- An event-based prospective memory (PM) task was employed.
- Thirty adult patients diagnosed with OCD participated.
- Thirty healthy adult participants served as the control group.
Main Results:
- OCD patients exhibited significantly greater reaction time (RT) costs during the ongoing task when given a PM instruction.
- A significant interaction between group and experimental condition indicated that PM instructions imposed an additional burden on OCD patients' ongoing task performance.
- A significant group difference was observed in PM task RTs, with OCD patients performing slower than healthy controls.
Conclusions:
- Patients with OCD experience significant difficulties with prospective memory tasks.
- These PM deficits in OCD appear to be linked to an overmonitoring of environmental stimuli for prospective memory cues.
- The findings suggest that cognitive remediation targeting overmonitoring may be beneficial for improving PM function in OCD.
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