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A validated method for standardization of the bark of Clerodendron serratum
Arunava Gantait1, Payel Roy, Neelesh Kumar Nema
1School of Natural Product Studies, Jadavpur University, Kolkata 700032, India.
Abstract:
Clerodendron serratum (Linn.) Moon (family: Verbenaceae) is used in Indian System of Medicine for asthma and cough. In the present study the extract of the bark of the plant was standardized using oleanolic acid as a marker. Methanolic extracts of the bark were prepared after defatting. HPTLC was used to quantify oleanolic acid in the extract. Percentage content of oleanolic acid in the methanolic extract was determined as 1.2% in contrast to the raw material at 0.058 % (Percentage yield of the extract 4.8%).
