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Updated: Jun 11, 2026

Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture
Published on: February 23, 2018
Label-free quantitative cell division monitoring of endothelial cells by digital holographic microscopy
Björn Kemper1, Andreas Bauwens, Angelika Vollmer
1University of Munster, Center for Biomedical Optics and Photonics, Robert-Koch-Strasse 45, Munster, 48149 Germany. bkemper@unimuenster.de
Abstract:
Digital holographic microscopy (DHM) enables quantitative multifocus phase contrast imaging for nondestructive technical inspection and live cell analysis. Time-lapse investigations on human brain microvascular endothelial cells demonstrate the use of DHM for label-free dynamic quantitative monitoring of cell division of mother cells into daughter cells. Cytokinetic DHM analysis provides future applications in toxicology and cancer research.

