Related Experiment Video
Updated: Jun 11, 2026

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
Published on: February 18, 2022
A more elaborative way to check codon quality: an open source program
Rakesh Kumar Shardiwal1, S S Sohrab
1Genseq Sdn Bhd, Cyberjaya 63000, Malaysia. shardiwal.rakesh@gmail.com
Abstract:
Relative Synonymous Codon Usage (RSCU) and Relative Adaptiveness of a Codon (RAC) table bias importance in gene expression are well documented in the literature. However, to improve the gene expression we need to figure out which codons are optimal for the expression in order to synthesise an appropriate DNA sequence. An alternative to the manual approach, which is obviously a tedious task, is to set up software on your computer to perform this. Though such kinds of programs are available on the internet, none of them are open-source libraries. Here, one can use our Perl program to do his or her task more easily and efficiently. It is free for everyone.
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