Related Experiment Video
Updated: Jun 11, 2026

08:20
Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
Published on: February 22, 2016
Predictive model for the size of bubbles and droplets created in microfluidic T-junctions
Volkert van Steijn1, Chris R Kleijn, Michiel T Kreutzer
1Prins Bernhardlaan 6, NL-2628 BW Delft, The Netherlands. V.vansteijn@tudelft.nl
Lab on a Chip
|July 10, 2010
Summary
Researchers developed a new formula to predict bubble and droplet size in T-junctions without needing experimental fitting. This breakthrough in microfluidics offers precise control over droplet and bubble generation for various applications.
Area of Science:
- Fluid dynamics
- Microfluidics
- Physical chemistry
Background:
- Microfluidic devices are widely used for generating bubbles and droplets.
- Existing models lack a physically sound, predictive expression for bubble and droplet size.
- Precise control over bubble and droplet dimensions is crucial for many applications.
Purpose of the Study:
- To develop a closed-form expression for predicting bubble and droplet size in T-junctions.
- To provide a theoretical model that explains the influence of T-junction geometry on droplet/bubble size.
- To enable tuning of T-junction shape for desired bubble and droplet dimensions.
Main Methods:
- Development of a theoretical model based on continuity, geometry, and pinch-off mechanisms.
- Derivation of a closed-form expression for bubble and droplet size prediction.
- Experimental validation using various T-junction shapes and multiphase microfluidic conditions.
Main Results:
- A novel, fitting-free closed-form expression for predicting bubble and droplet size was derived.
- The model successfully explains the strong dependence of size on T-junction shape.
- Experimental validation confirmed the model's accuracy for both gas bubbles and liquid droplets.
Conclusions:
- The presented theoretical model offers a simple yet effective method for predicting bubble and droplet size in T-junctions.
- T-junction geometry can be intentionally designed to control the size of generated bubbles and droplets.
- This work provides a valuable tool for optimizing microfluidic applications requiring precise droplet and bubble generation.

