Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...

The Effect of Aging on Tissues

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

Exercise and Muscle Performance

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of gestational stress on bone and body composition in Wistar rats after lactation.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica·2025

Same author

Ternary composites of poly(vinylidene fluoride-co-hexafluoropropylene) with silver nanowires and titanium dioxide nanoparticles as separator membranes for lithium-ion batteries.

Journal of colloid and interface science·2024

Same author

Reduced Handgrip Strength Is Associated with 1 Year-Mortality in Brazilian Frail Nonagenarians and Centenarians.

The Journal of frailty & aging·2024

Same author

Cost-Consequences Analysis Following Different Exercise Interventions in Institutionalized Oldest Old: A Pilot Study of a Randomized Clinical Trial.

The journal of nutrition, health & aging·2023

Same author

Letter to the editor: Dance as an Intervention to Improve Physical and Cognitive Functioning in Older Adults.

The journal of nutrition, health & aging·2023

Same author

Action potential variability in human pluripotent stem cell-derived cardiomyocytes obtained from healthy donors.

Frontiers in physiology·2023

Search research articles

Related Experiment Video

Updated: Jun 11, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Physiological effects of concurrent training in elderly men.

E L Cadore¹, R S Pinto, F L R Lhullier

¹Federal University of Rio Grande do Sul, Physical Education School, Porto Alegre, Brazil. edcadore@yahoo.com.br

International Journal of Sports Medicine

|July 10, 2010

Summary

Concurrent training in elderly men showed interference effects, potentially impairing neural adaptations. Strength training alone yielded superior gains in muscle strength and activation compared to combined or endurance training.

More Related Videos

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Related Experiment Videos

Last Updated: Jun 11, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Area of Science:

Exercise Physiology
Gerontology
Sports Science

Background:

Concurrent strength and endurance training is popular among older adults.
Understanding its impact on neuromuscular and hormonal factors is crucial for optimizing training programs in this demographic.

Purpose of the Study:

To investigate the effects of concurrent strength and endurance training on neuromuscular and hormonal parameters in elderly men.
To compare the outcomes of concurrent training with isolated strength or endurance training.

Main Methods:

23 healthy elderly men (65±4 years) were divided into concurrent (CG), strength (SG), or endurance (EG) groups.
Training programs were conducted 3 times per week for 12 weeks.
Evaluated parameters included muscle strength, muscle activation, and serum hormones.

Main Results:

All groups showed increased lower-body strength, with SG > CG > EG.
Only SG and CG improved upper-body strength.
SG demonstrated significant increases in isometric strength and maximal muscle activation, alongside decreases in submaximal activation.
EG experienced a decrease in free testosterone.

Conclusions:

Concurrent training may lead to an "interference effect" that impairs neural adaptations.
Isolated strength training appears more effective for enhancing muscle strength and activation in elderly men compared to concurrent or endurance training alone.