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Updated: Jun 11, 2026
09:01
The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques
Published on: July 3, 2014
Bovine respiratory coronavirus.
1Department of Veterinary Preventive Medicine, Food Animal Health Research Program, Ohio Agricultural Research and Development Center, College of Veterinary Medicine, The Ohio State University, Wooster, OH 44691, USA. saif.2@osu.edu
Summary
Bovine coronaviruses (BCoVs) cause significant respiratory and enteric diseases in cattle. This review focuses on respiratory BCoV infections, highlighting knowledge gaps in immunity and vaccines.
Area of Science:
- Veterinary Virology
- Infectious Diseases in Livestock
Background:
- Bovine coronaviruses (BCoVs) are significant pathogens causing respiratory and enteric diseases in cattle.
- BCoVs manifest as calf diarrhea, winter dysentery, and respiratory infections, including the bovine respiratory disease complex.
- Current diagnostic and vaccine strategies for respiratory BCoV infections are limited.
Purpose of the Study:
- To provide a comprehensive overview of respiratory bovine coronavirus infections in cattle.
- To review viral characteristics, epidemiology, diagnosis, pathogenesis, clinical signs, immunity, and vaccine development for BCoV.
Main Methods:
- Literature review focusing on scientific articles related to bovine coronaviruses.
- Synthesis of information on BCoV's impact on cattle health and disease management.
Main Results:
- BCoVs are pneumoenteric viruses infecting both the respiratory tract and intestines.
- No distinct markers differentiate BCoVs causing various clinical syndromes.
- Correlates of immunity and effective vaccines for respiratory BCoV infections are currently lacking.
Conclusions:
- Further research is needed to understand immunity and develop effective vaccines against respiratory BCoV.
- Improved diagnostic tools and targeted interventions are crucial for managing BCoV-associated diseases in cattle.
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