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Updated: Jun 11, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Hospital-acquired human bocavirus in infants
G S Durigon1, D B L Oliveira, S B Vollet
1Department of Paediatrics, Santa Casa de Misericórdia Hospital, São Paulo, Brazil. giuliana.durigon@gmail.com
Hospital-acquired human bocavirus (HBoV) infections are a concern in infants with respiratory illness. Screening for HBoV in hospital settings is recommended, particularly for intensive care units.
Area of Science:
- Pediatrics
- Virology
- Infectious Diseases
Background:
- Human bocavirus (HBoV) is a known respiratory pathogen in young children.
- Nosocomial infections pose a significant risk to hospitalized infants.
Purpose of the Study:
- To determine the incidence of hospital-acquired HBoV infections in infants hospitalized with respiratory infections.
- To compare characteristics of hospital-acquired HBoV with community-acquired cases.
Main Methods:
- Screening of 511 nasopharyngeal aspirates from infants hospitalized between January and December 2008.
- Identification of HBoV through laboratory analysis.
Main Results:
- Ten out of 55 HBoV infections identified were hospital-acquired.
- Coinfection with other respiratory viruses was infrequent in hospital-acquired HBoV cases.
Conclusions:
- HBoV is a potential cause of nosocomial respiratory infections in hospitalized children.
- Consideration of HBoV screening in hospital settings, especially ICUs, is warranted.
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