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Updated: Jun 11, 2026

Robot-Assisted Radical Antegrade Modular Pancreatosplenectomy Including Resection and Reconstruction of the Spleno-Mesenteric Junction
Published on: January 3, 2020
[Radical complications of obesity]
1CHU Hautepierre-Strasbourg, service de médecine interne, endocrinologie et nutrition, 1, avenue Molière, BP 83049, 67098 Strasbourg cedex, France. jean-louis.schlienger@chru-strasbourg.fr
Obesity causes numerous health problems due to excess fat tissue and inflammation. Many obesity-related diseases, including diabetes and heart disease, can be reversed with significant weight loss.
Area of Science:
- Internal Medicine
- Pathology
- Endocrinology
Context:
- Obesity is a complex condition characterized by excessive body fat accumulation.
- Increased adipose tissue mass and associated inflammation contribute to widespread morbidity.
- Abdominal fat, in particular, is linked to the overproduction of pro-inflammatory molecules.
Purpose:
- To outline the multifaceted health complications associated with obesity.
- To differentiate between complications linked to fat mass and inflammatory processes.
- To highlight the potential for reversibility of these conditions.
Summary:
- Obesity leads to increased morbidity through elevated fat tissue mass and pro-inflammatory molecule hyperproduction from abdominal fat.
- Key complications include cardiovascular disease, metabolic syndrome, diabetes mellitus, and arthritis.
- Other associated conditions encompass steatohepatitis, glomerulosclerosis, digestive issues, fertility problems, psychological dysfunction, and certain cancers.
Impact:
- Obesity poses significant risks for pregnancy and surgical outcomes.
- The majority of obesity-related health complications are reversible following substantial weight reduction.
- Understanding these links is crucial for public health strategies and clinical management.
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