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Updated: Jun 11, 2026
16:56
Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
Published on: August 30, 2014
Adherence issues related to sublingual immunotherapy as perceived by allergists
Silvia Scurati1, Franco Frati, Gianni Passalacqua
1Scientific and Medical Department, Stallergenes, Milan, Italy;
Patient Preference and Adherence
|July 13, 2010
Summary
Allergists believe patient perception of clinical efficacy, cost, and side effects are key to adherence with sublingual immunotherapy (SLIT). Improving patient information from prescribers can enhance SLIT treatment adherence.
Area of Science:
- Allergy and immunology
- Clinical research
- Patient adherence
Background:
- Sublingual immunotherapy (SLIT) is an effective treatment for allergic rhinitis and asthma.
- SLIT is self-administered, raising concerns about patient adherence.
- Understanding factors influencing adherence is crucial for optimizing SLIT outcomes.
Purpose of the Study:
- To evaluate allergists' perceptions of factors affecting patient adherence to SLIT.
- To identify key issues influencing patient compliance with sublingual immunotherapy.
Main Methods:
- A questionnaire-based survey was conducted among 296 Italian allergists.
- Allergists rated the importance of adherence issues using a Visual Analog Scale (VAS).
Main Results:
- Clinical efficacy was perceived as the most important factor for adherence (54%).
- Reimbursement (34%) and absence of side effects (21%) were also highly ranked.
- Patient education, follow-up, and ease of use were considered less critical by allergists.
Conclusions:
- Clinical efficacy, cost, and side effects are major perceived drivers of SLIT adherence.
- Enhancing patient information provided by prescribers may improve adherence to sublingual immunotherapy.
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