Related Experiment Videos
Effects of intracerebroventricular histamine injection on circadian activity phase entrainment during rapid
N Itowi1, A Yamatodani, T Mochizuki
1Department of Pharmacology II, Faculty of Medicine, Osaka University, Japan.
Neuroscience Letters
|February 11, 1991
Abstract:
Histamine is reported to have different effects on shifting the circadian activity phase depending on its circadian administration time (CT). The delay-sensitive period is CT 12-15, and the advance-sensitive period is CT 0-3. The activity phase of rats was entrained by a new light-dark cycle within a week in groups treated with either saline or i.c.v. histamine at CT 12-15. However, on treatment at CT 0-3 the activity phase of the group treated with histamine was entrained by the new light-dark cycle in half the period required for entrainment in the control group.