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Related Concept Videos

Action Potential01:14

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
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An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
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Induced Electric Fields01:23

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The fact that emfs are induced in circuits implies that work is being done on the conduction electrons in the wires. What can possibly be the source of this work? We know that it’s neither a battery nor a magnetic field, as a battery does not have to be present in a circuit where current is induced, and magnetic fields never do any work on moving charges. The source of the work is in fact an electric field that is induced in the wires. For example, if a stationary conductor is placed in a...

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Related Experiment Video

Updated: Jun 11, 2026

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

Endogenous electric fields may guide neocortical network activity.

Flavio Fröhlich1, David A McCormick

  • 1Department of Neurobiology, Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA.

Neuron
|July 14, 2010
PubMed
Summary
This summary is machine-generated.

Endogenous electric fields (EFs) can enhance and entrain neocortical network activity, even at physiological strengths. This suggests a feedback loop where neuronal activity influences EFs, potentially guiding brain function.

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Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

Published on: March 31, 2016

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Electrophysiology

Background:

  • Endogenous electric fields (EFs) are traditionally viewed as byproducts of neural activity.
  • External EFs can influence network activity in the hippocampus.
  • The role of endogenous EFs in physiological neocortical activity remains largely unexplored.

Purpose of the Study:

  • To investigate the role of endogenous electric fields (EFs) in physiological neocortical network activity.
  • To determine if weak EFs can modulate neocortical activity during slow oscillations.
  • To explore the potential feedback loop between neuronal activity and endogenous EFs.

Main Methods:

  • Utilized an in vitro neocortical slow oscillation model.
  • Applied weak sinusoidal and naturalistic electric fields (EFs).
  • Investigated real-time modulation of network activity by feedback fields.

Main Results:

  • Weak EFs, within the range of endogenous field strengths, enhanced and entrained physiological neocortical network activity.
  • Identified an amplitude threshold for EF modulation.
  • Demonstrated real-time feedback between neuronal activity and endogenous EFs.

Conclusions:

  • Endogenous electric fields (EFs) can significantly influence and guide neocortical network activity.
  • A feedback loop exists between neuronal activity and endogenous EFs.
  • The susceptibility of active networks to EFs suggests a functional role beyond epiphenomena.