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Longitudinal medication usage in Alzheimer disease patients

Carolyn W Zhu1, Elayne E Livote, Kristin Kahle-Wrobleski

  • 1*This Geriatric Research, Education, and Clinical Center (GRECC) and HSR&D Center for the Study of Health Care Across Systems and Sites of Care, James J. Peters VA Medical Center, Bronx †Brookdale Department of Geriatrics, Mount Sinai School of Medicine ∥Gertrude H. Sergievsky Center and the Department of Neurology, Columbia University Medical Center **Department of Psychology, Mount Sinai School of Medicine ‡Eli Lily & Company §Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, New York, NY ¶Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD ♯Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Alzheimer Disease and Associated Disorders
|July 14, 2010
PubMed
Summary

Cholinesterase inhibitors (ChEIs) use declined while memantine use increased in Alzheimer disease (AD) patients over six years. ChEI use correlated with better function, while memantine use linked to better function but poorer cognition.

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