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Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...

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Related Experiment Video

Updated: Jun 11, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

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Published on: May 12, 2023

Failure to vaccinate.

Sara Bird1

  • 1Medico-Legal and Advisory Services, MDA National. sbird@mdanational.com.au

Australian Family Physician
|July 15, 2010
PubMed
Summary

Overwhelming postsplenectomy infection caused a patient's death. This case underscores the critical need for regular vaccinations and patient education for individuals without a spleen.

Area of Science:

  • Medical Negligence
  • Infectious Diseases
  • Immunology

Background:

  • Medicolegal referrals and case histories are utilized, with modifications for anonymity.
  • Focuses on a fatal case of overwhelming postsplenectomy infection.

Observation:

  • A patient died due to severe infection following spleen removal.
  • The infection was identified as overwhelming postsplenectomy infection.

Findings:

  • The patient's death was directly linked to postsplenectomy infection.
  • Lack of adequate vaccination and patient awareness contributed to the fatal outcome.

Implications:

  • Highlights the critical importance of timely vaccinations for asplenic patients.

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  • Emphasizes the necessity of comprehensive patient education regarding infection risks after splenectomy.
  • Underscores the role of preventative healthcare in managing asplenic individuals.