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A comparative study of root coverage using two different acellular dermal matrix products.

Thomas S Barker1, Marco A Cueva, Francisco Rivera-Hidalgo

  • 1Department of Periodontics, Texas A&M Health Science Center, Baylor College of Dentistry, Dallas, TX 75246, USA.

Journal of Periodontology
|July 16, 2010
PubMed
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Both Alloderm (ADM) and Puros Dermis (PDM) acellular dermal matrices effectively treat gingival recession, showing similar root coverage and healing outcomes in a 6-month study.

Area of Science:

  • Periodontology
  • Regenerative Dentistry
  • Biomaterials Science

Background:

  • Gingival recession presents significant esthetic challenges in dentistry.
  • The efficacy of new acellular dermal matrix (ADM) materials requires comparison with established options.
  • Alloderm (ADM) and Puros Dermis (PDM) are ADMs used for root coverage.

Purpose of the Study:

  • To compare the clinical outcomes of root coverage using a coronally advanced flap with either Alloderm (ADM) or Puros Dermis (PDM) for localized gingival recession.
  • To evaluate the effectiveness of ADM in treating gingival recession and improving periodontal health.

Main Methods:

  • A split-mouth design was employed with 52 contralateral sites in 14 patients with Miller Class I or III facial tissue recession.
  • Twenty-six sites received a coronally advanced flap with PDM, and 26 sites received a coronally advanced flap with ADM.

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  • Clinical measurements including vertical recession, keratinized tissue, probing depths, and attachment levels were recorded at baseline, 3 months, and 6 months.
  • Main Results:

    • Both PDM and ADM groups demonstrated significant improvements in root coverage, with mean coverages of 2.83 mm (PDM) and 3.13 mm (ADM).
    • The percentage of root coverage achieved was 81.4% for PDM and 83.4% for ADM.
    • No statistically significant differences were observed between the two materials regarding root coverage, probing depth, or keratinized tissue.

    Conclusions:

    • No statistical or clinical difference exists between Alloderm (ADM) and Puros Dermis (PDM) when used with coronally advanced flaps for root coverage.
    • Both acellular dermal matrix materials are equally successful in achieving root coverage and improving periodontal parameters.