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Updated: Jun 11, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Pharyngeal disturbances in OSAS patients before and 1 year after UPPP
Karin Lundkvist1, Danielle Friberg
1Department of Otorhinolaryngology, Karolinska University Hospital, Huddinge, Stockholm and Clintec, Karolinska Institute, Sweden. karin.lundkvist@karolinska.se
Conclusions:
The results indicate that conservative uvulopalatopharyngoplasty with tonsillectomy (UPPP) did not change the degree of pharyngeal disturbances in patients with obstructive sleep apnea syndrome (OSAS).
Objectives:
To investigate if the symptom scores of pharyngeal disturbances in OSAS patients were changed 1 year after UPPP, by using a questionnaire pre- and postoperatively, and to compare with healthy non-snoring controls.
Methods:
Fifty men and eight women, median age 46 years (range 25-75), median body mass index (BMI) 28 kg/m2 (20-38), and median preoperative oxygen desaturation index 16 (7-100) were included as they had all failed non-surgical treatment and wanted pharyngeal surgery. The questionnaire consisted of 10 questions with 4 degrees of disturbances; the maximum score was 30 and was evaluated before and 1 year after surgery. Fifteen age-, gender- and BMI-matched controls responded to the same questionnaire.
Results:
Responses to the questionnaire were provided pre- and postoperatively by 47 of 58 patients (81%). Their median score was unchanged from 5 (range 0-17) to 5 (0-19), compared with controls 1 (0-3). Analyses of separate questions showed a significant decrease in the score for 'globus sensation' and 'swelling' postoperatively.
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