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Published on: March 17, 2014
Chronic eosinophilic pneumonia with mucous plugs in a child
Erkan Cakir1, Ferda Aksoy, Fatma Betül Cakır
1Sureyyapasa Chest Diseases and Thoracic Surgery Training and Investigation Hospital, Department of Pediatric Pulmonology, Istanbul, Turkey. erkancakir1@yahoo.com
Insights
This case study highlights a rare pediatric lung disease, chronic eosinophilic pneumonia, presenting uniquely with mucous plugs. Early diagnosis and corticosteroid treatment led to a significant recovery in a young patient.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Rare Diseases
Background:
- Chronic eosinophilic pneumonia (CEP) is an uncommon cause of persistent lung issues in children.
- CEP diagnosis can be challenging due to varied presentations and the need to exclude other eosinophilic lung diseases.
Observation:
- A 7-year-old girl presented with a 5-year history of cough and sputum, exhibiting bilateral alveolar infiltrates and ground-glass opacities.
- Peripheral eosinophilia and mucous plugs found during bronchoscopy were key diagnostic indicators.
- Bronchoalveolar lavage confirmed hypereosinophilia, supporting the diagnosis of CEP.
Findings:
- The patient was diagnosed with idiopathic chronic eosinophilic pneumonia after excluding other causes.
- A remarkable improvement was observed following treatment with oral corticosteroids.
Implications:
- This case is the first documented instance of pediatric chronic eosinophilic pneumonia presenting with mucous plugs.
- Highlights the importance of considering CEP in children with persistent respiratory symptoms and eosinophilia, even with unusual findings like mucous plugs.
- Emphasizes the efficacy of corticosteroids in managing this rare pediatric lung condition.
Abstract:
Chronic eosinophilic pneumonia is a rare cause of chronic lung disease in children. A 7-year-old girl who attended our clinics with cough and sputum lasting for 5 years, has been evaluated for bilateral alveolar infiltration and ground-glass opacities. Peripheral eosinophilia was detected in total cell blood count. Flexible bronchoscopy showed mucous plugs. Bronchoalveolar lavage fluid and cell block of mucous plugs determined hypereosinophilia. Chronic eosinophilic pneumonia was confirmed after the elimination of other eosinophilic lung diseases and the case was accepted to be idiopathic. She showed a dramatic response to oral corticosteroids. This is the first reported case of chronic eosinophilic pneumonia presenting with mucous plugs in children described to date in the literature.
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