Related Experiment Video
Updated: Jun 10, 2026
Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
Published on: April 27, 2014
Repetitive transcranial magnetic stimulation or transcranial direct current stimulation?
Alberto Priori1, Mark Hallett, John C Rothwell
1Dipartimento di Scienze Neurologiche, Università degli Studi di Milano, Centro Clinico per le Neuronanotecnologie e la Neurostimolazione, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy. alberto.priori@unimi.it
Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are noninvasive brain stimulation techniques. This article guides researchers in choosing between rTMS and tDCS for their specific work.
Area of Science:
- Neuroscience
- Neuromodulation
- Brain Stimulation Techniques
Background:
- Noninvasive brain stimulation methods like repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are increasingly accessible.
- Both rTMS and tDCS can induce lasting changes in cortical excitability beyond the stimulation period.
Purpose of the Study:
- To theoretically discuss factors influencing the choice between rTMS and tDCS.
- To aid researchers in selecting the most appropriate neuromodulation technique for their experimental or therapeutic goals.
Main Methods:
- Theoretical discussion comparing rTMS and tDCS.
- Analysis of factors relevant to technique selection in neuromodulation research.
Main Results:
- Both rTMS and tDCS offer noninvasive cortical stimulation with prolonged after-effects.
- The choice between rTMS and tDCS depends on specific research or clinical objectives.
Conclusions:
- Understanding the theoretical underpinnings and practical considerations of rTMS and tDCS is crucial for effective application.
- This comparative analysis aims to optimize the selection of neuromodulation techniques for neuroscience, neurology, psychiatry, rehabilitation, and pain management.
