Contrast sensitivity comparison between AcrySof ReSTOR and Acri.LISA aspheric intraocular lenses

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Optics

Background:

• Intraocular lenses (IOLs) are crucial for vision restoration after cataract surgery.
• Assessing contrast sensitivity is vital for evaluating visual function under various lighting conditions.
• Aspheric IOL designs aim to improve visual quality, but their performance in mesopic conditions requires thorough evaluation.

Purpose of the Study:

• To compare the distance contrast sensitivity of AcrySof ReSTOR and Acri.LISA aspheric intraocular lenses (IOLs).
• To evaluate IOL performance under photopic, mesopic, and mesopic with glare conditions.
• To determine if significant differences exist between these two IOL models in contrast sensitivity post-implantation.

Main Methods:

• Contrast sensitivity was measured using the Optec 6500 FACT chart in patients implanted with either AcrySof ReSTOR SN6AD3 or Acri.LISA 366D IOLs.
• Testing was conducted under three lighting conditions: photopic (85 cd/m2), mesopic (3 cd/m2), and mesopic with glare.
• Binocular contrast sensitivity was assessed at 1 and 6 months post-surgery.

Main Results:

• Both AcrySof ReSTOR and Acri.LISA IOLs provided excellent distance and near visual acuity (approximately 20/20).
• Contrast sensitivity was within the normal range under photopic conditions for both IOLs.
• A reduction in contrast sensitivity, particularly at higher spatial frequencies, was observed under mesopic conditions for both IOLs, with no statistically significant differences between them.

Conclusions:

• The AcrySof ReSTOR SN6AD3 and Acri.LISA aspheric IOLs exhibit comparable performance in terms of contrast sensitivity.
• Both IOLs maintain normal contrast sensitivity in photopic conditions.
• A decrease in contrast sensitivity under mesopic conditions is noted for both IOLs, highlighting a common characteristic rather than a difference between the brands.