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Updated: Jun 10, 2026

Investigating the Phagocytosis of Leishmania using Confocal Microscopy
Published on: July 29, 2021
Structure, functions, and biosynthesis of glycoconjugates of Leishmania spp. cell surface
1Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. nnovogilov@gmail.com
Abstract:
Cell surface of leishmaniasis causal agent, a parasitic member of Protozoa of Leishmania genus, is covered by thick glycocalix consisting of various phosphatidylinositol-anchored molecules. This review deals with the structure and biosynthesis of the main phosphoglycans and glycoproteins of Leishmania cell surface, many of which incorporate the rare natural D-arabinopyranose, and the problem concerning the involvement of these molecules in support of Leishmania survival during their intricate life cycle is discussed.
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