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Acylated ghrelin increases after controlled short-time exercise in school-aged children
W Sauseng1, B Nagel, A Gamillscheg
1Department of Pediatrics, Division of General Pediatrics, Medical University of Graz, Graz, Austria.
Scandinavian Journal of Medicine & Science in Sports
|July 20, 2010
Summary
Exercise significantly increases acylated ghrelin, an appetite hormone, in children. This hormonal response may encourage calorie intake after physical activity in young individuals.
Area of Science:
- Pediatric Endocrinology
- Exercise Physiology
- Appetite Regulation
Background:
- Ghrelin, a peptide hormone, is crucial for appetite regulation.
- The impact of exercise on ghrelin levels in children and adolescents remains unclear.
Purpose of the Study:
- To investigate the acute effects of controlled exercise on acylated and total ghrelin concentrations in school-aged children.
- To explore correlations between ghrelin response, exercise duration, and maximal performance.
Main Methods:
- A controlled bicycle exercise test was administered to 36 healthy school-aged children.
- Plasma ghrelin concentrations (acylated and total) were measured before and immediately after exercise.
- A control group of 24 healthy children was included for comparison.
Main Results:
- Acylated ghrelin concentrations increased significantly post-exercise compared to the control group (P<0.001).
- Total ghrelin concentrations showed no significant change after exercise.
- A positive correlation was observed between the increase in acylated ghrelin and both exercise duration (P<0.01) and maximal performance (P<0.01).
Conclusions:
- Controlled exercise significantly elevates acylated ghrelin levels in school-aged children.
- This increase in acylated ghrelin may represent a physiological mechanism to stimulate caloric intake following energy expenditure.
- Findings highlight a potential link between physical activity and appetite regulation in pediatric populations.
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